Durham medtech startup Xilis raises $70M; Google Ventures, Duke Angels among backers

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Xilis, a startup founded by two professors at Duke University focusing on technology to boost precision health and oncology, has landed $70 million in new funding with Google Ventures among the backers.

The two-year-old company had previously raised close to $5 million.

“Our vision is to transform cancer care in diagnostics and reshape drug development by providing a technology for rapid therapeutic profiling,” said Xiling Shen, founder and CEO of Xilis, in Thursday’s announcement.. “The support provided by these world-class investors is an important milestone for our journey to transform cancer care and dramatically improve patient survival by enabling personalized precision oncology and bringing transformative medicines to patients faster and with higher success rates.”

Xilis koncentruje się na technologii MicroOrganoSphere (MOS), która nie tylko pomaga w dostarczaniu precyzyjnych terapii pacjentom chorym na raka, ale także przyspiesza odkrywanie i rozwój leków.


Opatentowana technologia MicroOrganoSpher (MOS) firmy Xilis obejmuje miniaturowe nowotwory pacjentów, które wychwytują pełne mikrośrodowisko i niejednorodność oraz zapewniają zautomatyzowane i skalowalne rozwiązanie. Korzystając z algorytmów opartych na MOS i sztucznej inteligencji, Xilis opracowuje dla kliniki Xilis Response Score™, umożliwiający onkologom podejmowanie świadomych i terminowych decyzji dotyczących leczenia. Ponadto technologia MOS przyspiesza rozwój i badania kliniczne leków przeciwnowotworowych, umożliwiając analizę autentycznych mikrośrodowisk nowotworu, wysokoprzepustowe modelowanie przedkliniczne i możliwości selekcji pacjentów klinicznych.

Mubadala Capital led the round.

The Duke Angel Network also participated.

LSP in Europe, Catalio Capital Management and previous nvestors Felicis Ventures, Two Sigma Ventures, Pear VC, KdT Ventures, and Alix Ventures also joined the funding.

Shen, David Hsu and Hans Clevers founded the company. Clevers invented the “organoid” technology and also is a venture partner at LSP. Shen and Hsu teach at Duke University.

“Since my lab invented organoids a dozen years ago, we provided proof-of-concept for many applications, yet the technology remained slow, complex, and expensive,” Clevers said in a statement. ” Together with LSP, I have been looking for enabling technology to unlock the full potential, and Dr. Shen and Dr. Hsu’s invention of the MOS technology has torn down those hurdles and will accelerate its use both in the clinic and for drug discovery and development.”

The funds will be used “to further advance Xilis’ proprietary MOS technology, expand its AI-driven capabilities, fund clinical studies for diagnostic development, and validate the use of MOS technology with biopharma partners,” the company said.

“Genetic approaches to cancer diagnostics continue to be impactful, and Xilis is creating meaningful pathways for its Precision Oncology Platform to improve cancer care for a broader set of patients,” said Google Ventures (GV) Managing Partner Krishna Yeshwant. “Xilis brings together experts in the fields of organoid development and precision medicine, and I’m excited to work with this impressive team as they continue to develop a breakthrough approach.”

Pierwotnym źródłem: WRALTechWire